PilotEdit

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 Windows editor for huge files

 Author:   PilotEdit
 Homepage: http://www.pilotedit.com/
 Download: http://www.pilotedit.com/index.php?option=com_content&view=section&layout=blog&id=8&Itemid=56
 Family:   CuaFamily
 Platform: Windows
 License:  Freeware (for PilotEdit Lite) or Commercial (for PilotEdit and PilotEdit x64

This editor's speciality is editing large files. However, it appears capable of being an FTP client, work with encrypted files, and even perform compare/diff/merge of files and directories. It also does hex editor.

 Screenshot: