SkEdit

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 An HTML/Web? editor for MacOS?/X.

 Author:   Sean Kelly
 Homepage: http://www.skti.org/skEdit.php
 Family:   MacintoshEditorFamily, HTMLEditorFamily
 Platform: Mac OS/X
 License:  Shareware

It has a built-in Site manager, file manager, S/FTP client, and loads of other features geared towards web development. It also has SyntaxColorHighlighting?, LineNumbering?, and AutoCompletion?.

 Screenshot: